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Genetics

  • Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

    Analysis of variation in 51 human populations reveals details of European subpopulations and confirms that humans formed a chain of colonies as they radiated out from Africa.

  • The Fires of Aging

    Drawing on findings from a wide range of disciplines, the author identifies reduced levels of inflammation as a crucial factor in the recent increase in human life-spans.

  • Dwarfism, Where Pericentrin Gains Stature

    Mutations in a protein that functions in cell division result in human growth disorders, possibly by connecting DNA damage signaling and centrosome dysfunction.

  • Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism

    In humans, an inherited condition with small brain size and near-normal intelligence is caused by mutations that disrupt chromosome separation during cell division.

  • An Association Between the Kinship and Fertility of Human Couples

    The extensive genealogies of the Icelandic people show that couples who are 3rd or 4th cousins have more children and grandchildren than couples whose relationships are more or less distant.

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