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Genetics

  • Genome Sequence of Aedes aegypti, a Major Arbovirus Vector

    The genome of the mosquito that carries dengue and yellow fever consists of almost 50 percent transposable elements and over 15,000 protein-coding genes.

  • A Common Allele on Chromosome 9 Associated with Coronary Heart Disease

    About one of every four Caucasians carry a sequence variation at a regulatory region of chromosome 9 that confers an elevated risk of heart disease.

  • RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription

    Analysis of all the RNA transcribed from the human genome reveals three new classes of RNA that may be functionally important.

  • A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction

    About one of every four Caucasians carry a sequence variation at a regulatory region of chromosome 9 that confers an elevated risk of heart disease.

  • Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels

    The hereditary component of type 2 diabetes reflects the contribution of at least 10 genetic variants, each with a modest effect on risk.

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