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Genetics

  • Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

    Regions under strong selection in the human genome identify noncoding regulatory elements with possible roles in disease.

  • NIH Effort Gambles on Mysterious Extracellular RNAs

    A $17 million research program, announced this month by the U.S. National Institutes of Health, aims to determine whether RNA molecules are deliberately released by cells as hormonelike signals—and whether such extracellular RNAs can be harnessed for diagnosis and treatment of human diseases.

  • Random Sample

    Unlike most organisms, the springtail—a tiny, six-legged noninsect—gets smaller as it gets older, if temperatures are on the rise. And footage from the deep reveals how one deep-sea squid uses its tentacle clubs in an unusual way to lure its prey.

  • Mysterious Ribosomopathies

    Ribosomes are essential in all cell types, yet mutations to ribosomal proteins or assembly factors cause tissue-specific disease.

  • Random Sample

    To help slow the spread of the ash dieback fungus in the United Kingdom, scientists launch a new Facebook-based game in which players help identify genetic variations in the genomes of both fungus and trees. And the Federation of American Societies for Experimental Biology announces its "BioArt" winners for 2013.

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