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Genetics

  • Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project

    Extensive analysis of the Caenorhabditis elegans genome reveals regions highly occupied by multiple transcription factors.

  • Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

    The Drosophila modENCODE project demonstrates the functional regulatory network of flies.

  • Genetic Analysis Points the Way to Individualized PSA Tests

    Some men with high levels of prostate-specific antigen don't have prostate cancer, leading to unnecessary biopsies, and some with low PSA levels do. This week, a group in Iceland suggests individualizing healthy and high levels for each man tested by focusing on genetic variants that affect PSA levels.

  • The Runners-Up

    This year's runners-up for Breakthrough of the Year include a synthetic genome, the Neandertal genome, next-generation genomics, souped-up cellular reprogramming, exome sequencing, quantum simulators, molecular dynamics simulations, knockout rats, and HIV prophylaxis.

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