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Genetics

  • Cloned Neandertals Still in the Realm of Sci-Fi

    Since the idea of sequencing the Neandertal genome became more than a glimmer in a paleogeneticist's eye, some have asked, "Could we, should we, would we, bring this extinct human species back to life?" But for both technical and ethical reasons, experts say, bringing back a Neandertal is a pipe dream.

  • Computer Kid Makes Good

    Everyone involved in the Neandertal sequencing project at the Max Planck Institute for Evolutionary Anthropology stresses the teamwork involved in sequencing the Neandertal genome. And yet Richard "Ed" Green, the postdoctoral fellow in charge, still stands out.

  • Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture

    Array capture of Neandertal DNA identifies amino acid substitutions that occurred after the split between humans and Neandertals.

  • The Genome of the Western Clawed Frog Xenopus tropicalis

    Assembly, annotation, and analysis of the frog genome compares gene content and synteny with the human and chicken genomes.

  • Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing

    Genomic sequencing of an entire family reveals the rate of spontaneous mutations in humans and identifies disease genes.

  • Mutations in DCC Cause Congenital Mirror Movements

    Humans who display involuntary symmetrical limb movements carry mutations in a gene required for nerve growth across the midline.

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