ArticlesScientific Apparatus and Laboratory Methods

A METHOD OF OBTAINING RENAL VENOUS BLOOD IN UNANESTHETIZED PERSONS WITH OBSERVATIONS ON THE EXTRACTION OF OXYGEN AND SODIUM PARA-AMINOHIPPURATE

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Science  04 Aug 1944:
Vol. 100, Issue 2588, pp. 108-110
DOI: 10.1126/science.100.2588.108

Abstract

Catheterization of the renal vein offers a safe and relatively simple method of obtaining blood as it leaves the kidney in the resting unanesthetized human subject.

In preliminary observation on 8 subjects the renal arteriovenous oxygen difference varied from 1.9 to 2.8 volumes per cent., averaging 2.3 volumes per cent. Sodium para-amino hippurate, at low plasma levels, was 88 per cent. extracted during a single circulation through the kidney.