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ORAL PENICILLIN WITH BASIC ALUMINUM AMINOACETATE

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Science  15 Jun 1945:
Vol. 101, Issue 2633, pp. 618-619
DOI: 10.1126/science.101.2633.618

Abstract

This method appears to be suitable for the oral administration of penicillin. Basic aluminum aminoacetate seems admirably suited for this purpose. It is neutral and buffers gastric acidity to pH 4 to 4.5. While this work was in progress McDermott et al.6 successfully employed magnesium trisilicate in this manner.

Clinical work is now in progress using the combination in infections known to be susceptible to parenteral penicillin therapy.