ArticlesSpecial Article

ORAL ADMINISTRATION OF PENICILLIN IN CORN OIL AND LANOLIN

Science  20 Jul 1945:
Vol. 102, Issue 2638, pp. 66-67
DOI: 10.1126/science.102.2638.66

Abstract

Oral administration of penicillin suspended in equal parts of corn oil and lanolin extends the maintenance of the penicillin level in the system (as determined by urine bio-assay). Measurable quantities were found 24 to 42 hours after ingestion.

Recovery of the penicillin is about five times higher than under administration in saline solution.

We wish to express our sincere appreciation to the various members of our staff who volunteered as subjects for these experiments.

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