Technical Papers

Effect of Methionine Supplements on Hepatic Injury Produced by Carbon Tetrachloride

Science  15 Feb 1946:
Vol. 103, Issue 2668, pp. 199-201
DOI: 10.1126/science.103.2668.199


At the present time the experimental evidence demonstrates that supplements of methionine will decrease the degree of liver damage produced by toxic agents in protein-depleted animals. In animals receiving a normal protein intake of 20-per cent or 41-per cent casein, methionine supplements did not decrease the degree of hepatic damage produced by carbon tetrachloride as judged by serum phosphatase values or bromsulphalein retention.