Technical Papers

The Effect of B-Pyracin and the Lactobacillus casei Factor Upon Hemoglobin Regeneration Following Hemorrhage

See allHide authors and affiliations

Science  08 Mar 1946:
Vol. 103, Issue 2671, pp. 303-304
DOI: 10.1126/science.103.2671.303


In severe experimental hemorrhagic anemia in hens, the injection of β-pyracin and Lactobacillus casei factor, alone and in combination, was found to hasten the regeneration of hemoglobin. When these factors were administered together, however, the rise in hemoglobin was much more rapid and the level reached was higher than in the lots administered the factors alone. The hemoglobin levels in the control lots rose above the "pre-bleeding" values and then began an almost immediate decline to approximately the original level. In the lots receiving β-pyracin and Lactobacillus casei factor, alone or in combination, the hemoglobin levels also rose above the "pre-bleeding" values but were maintained for some time after injections were discontinued before declining to the original values.