Technical Papers

Distemperoid Virus Interference in Canine Distemper

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Science  26 Apr 1946:
Vol. 103, Issue 2678, pp. 497-498
DOI: 10.1126/science.103.2678.497


A distemper virus modified by ferret passage so as to become a harmless vaccine for foxes and dogs exhibits the interference or cell-blockade phenomenon with respect to a virulent distemper infection in foxes. Ten control foxes receiving virulent distemper virus died, while 30 foxes receiving distemperoid virus in addition lived.