Technical Papers

The Activity of Synthetic Folic Acid in Purified Rations for the Chick

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Science  07 Jun 1946:
Vol. 103, Issue 2684, pp. 682-684
DOI: 10.1126/science.103.2684.682


The addition of 25γ of synthetic folic acid per 100 grams of our basal ration prevents the reduced growth, poor feathering condition, and low hemoglobin and hematocrit values consistently obtained when the basal ration is fed to chicks. More than 25γ are needed when the diet contains sulfasuxidine. Evidence for the possible indirect action of folic acid is summarized.

Vitamin C or whole liver powder gives a slight response in the presence of adequate amounts of synthetic folic acid.