ArticlesIn the Laboratory

A Useful Selective Bactericidal Property of Tergitol-7

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Science  28 Jun 1946:
Vol. 103, Issue 2687, pp. 758-759
DOI: 10.1126/science.103.2687.758


Starch tryptone agar containing 1 : 20,000 Tergitol-7 was successfully sterilized in the Arnold by one 30-minute heating period. Decreasing the concentration to 1 : 30,000 resulted in 4 per cent failures.

A concentration of 1 : 20,000 in the cold killed spores of B. mycoides and an unidentified heat-resistant bacillus but failed to kill spores of B. subtilis.

Concentrations of 1 : 30,000 permitted growth after sterilization of all species of Streptomyces which were tested, while concentrations of 1 : 20,000 permitted growth of all species but one.

Concentrations of 1 : 20,000 did not inhibit the growth of selected species of Penicillium and Aspergillus or of Staph. aureus.

Concentrations as high as 1 : 10,000 did not inhibit the growth of E. coli.