Technical Papers

Urinary Recovery of Penicillin After Oral Administration With Antacids and Buffers

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Science  02 Aug 1946:
Vol. 104, Issue 2692, pp. 102-104
DOI: 10.1126/science.104.2692.102

Abstract

Combinations of sodium bicarbonate, colloidal kaolin, magnesium trisilicate, and bismuth subcarbonate with penicillin produce a higher penicillin titer in the urine than the various antacids and buffers recommended for oral penicillin therapy.