ArticlesIn the Laboratory

A Simple, Rapid Technique for the Study of the Action of Hydrolytic Enzymes on Insoluble Substrates

See allHide authors and affiliations

Science  22 Nov 1946:
Vol. 104, Issue 2708, pp. 488-490
DOI: 10.1126/science.104.2708.488


A rapid, simple, quantitative technique has been developed for the study of the action of hydrolytic enzymes on certain insoluble substrates. The end point of digestion is indicated by the release of a glass bead, when two pieces of lens paper sealed together by the substrate separate due to its digestion by the enzyme.