Physicochemical Study in Water of a Mucoprotein with Virus-Inhibiting Activity

See allHide authors and affiliations

Science  31 Oct 1958:
Vol. 128, Issue 3331, pp. 1087-1088
DOI: 10.1126/science.128.3331.1087


Human urinary mucoprotein precipitated with cetyltrimethylammonium bromide and suspended in distilled water has a light-scattering molecular weight of 2.8 x 106, an intrinsic viscosity of 225, a refractive index increment of 1.73 x 10 4, and an absorption coefficient (E5" ,,) of 11.4. The molecule is therefore smaller than that of the mucoprotein isolated by Tamm and Horsfall but retains its biological activity.