Cobalt Activation of Fatty-Acid Synthesis in Yeast Homogenates

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Science  07 Nov 1958:
Vol. 128, Issue 3332, pp. 1135-1136
DOI: 10.1126/science.128.3332.1135-a


The incorporation of acetate into lipids in homogenates of Saccharomyces cerevisiae was inhibited at low concentrations of ethylenediaminetetraacetate, under both aerobic and anaerobic conditions. Of various cations tested, none could effectively reverse this inhibition. However, Co++ completely restored the synthesis of fatty acids, but not of nonsaponifiable lipids.