An Immunological Investigation of Human Pituitary Growth Hormone

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Science  21 Nov 1958:
Vol. 128, Issue 3334, pp. 1276-1277
DOI: 10.1126/science.128.3334.1276


Growth hormone isolated from human pituitaries has been demonstrated to be a good antigen in the rabbit. With the rabbit antiserum to human somatotropin, it is possible to detect as little as 0.1 µg of the hormone by precipitin test. The antiserum was also capable of neutralizing the growth-promoting activity of human somatotropin.