Airborne Immunization against Tuberculosis

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Science  21 Nov 1958:
Vol. 128, Issue 3334, pp. 1282-1283
DOI: 10.1126/science.128.3334.1282


Inhalation of very small numbers of living attenuated (BCG) organisms and their multiplication in guinea pigs results in the development of acquired resistance against subsequent airborne infection with virulent tubercle bacilli. Different strains of BCG have differing capacities to immunize by this means.