Oxygen Isotope Fractionation in Reactions Catalyzed by Enzymes

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Science  16 Jan 1959:
Vol. 129, Issue 3342, pp. 146-147
DOI: 10.1126/science.129.3342.146


A study has been made of some of the enzymatic mechanisms responsible for the previously reported fractionation of oxygen isotopes by whole organisms. The data indicate that the fractionation occurs through the activity of metalloenzymes.