Ammonia Excretion by Mammalian Lung

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Science  30 Jan 1959:
Vol. 129, Issue 3344, pp. 270-271
DOI: 10.1126/science.129.3344.270


The intravenous administration of ammonium acetate to dogs results in measurable levels of free ammonia in expired air. Simultaneous measurement of the physiologic dead space permits the calculation of the partial pressure of ammonia in alveolar air. This finding has implications for ammonium metabolism and transport.