Second Spectroscopically Abnormal Methemoglobin Associated with Hereditary Cyanosis

Science  13 Feb 1959:
Vol. 129, Issue 3346, pp. 393-394
DOI: 10.1126/science.129.3346.393


Isolation of an abnormal methemoglobin from two families exhibiting dominantly transmitted cyanosis have permitted the recognition of two different pigments of the hemoglobin M type. It is possible that the abnormal properties which characterize the acidic methemoglobin derivatives result from a crevice configuration of the heme, with two Feprotein bonds.