Fluorescence of Tryptophan Derivatives in Trifluoroacetic Acid

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Science  06 Mar 1959:
Vol. 129, Issue 3349, pp. 641-643
DOI: 10.1126/science.129.3349.641


Solutions of tryptophan-containing proteins in trifluoroacetic acid (TFA) develop green fluorescence. Studies have been made of the effect of TFA on tryptophan and tryptophan derivatives, and a dihydro-β-carboline has been identified among the fluorescent products.