Ascites Induced in Mice by Staphylococcus

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Science  20 Mar 1959:
Vol. 129, Issue 3351, pp. 775
DOI: 10.1126/science.129.3351.775


Ascitic fluid containing high titers of antibody was induced in mice by Staphylococcus. Two to three intraperitoneal inoculations of 0.3 ml of a killed suspension of S. aureus mixed with complete Freund's adjuvant, given at 5-day intervals, produced ascites in 100 percent of the mice tested.