Biochemical Basis of Mating in Yeast

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Science  10 Apr 1959:
Vol. 129, Issue 3354, pp. 960-961
DOI: 10.1126/science.129.3354.960


One mating type of the yeast Hansenula wingei possesses a specific protein on its cell surface which is complementary to a specific polysaccharide on the cell surface of the opposite mating type. The initial phase of mating in which cells of opposite types combine is therefore analogous to a reaction between an antibody and a polysaccharide antigen.