Free β-Hydroxy-γ-amino-butyric Acid in Brain

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Science  01 May 1959:
Vol. 129, Issue 3357, pp. 1225-1226
DOI: 10.1126/science.129.3357.1225


By using the methods of paper chromatography and high-potential paper electrophoresis and by comparing the pattern of prepared extracts with that of synthesized β-hydroxy-γ-aminobutyric acid, we found that free β-hydroxy-γ-aminobutyric acid exists in the brains of mice, rabbits, cattle, and human beings.