Prolongation of Response of Node of Ranvier by Metal Ions

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Science  15 May 1959:
Vol. 129, Issue 3359, pp. 1366-1367
DOI: 10.1126/science.129.3359.1366


The response of the node of Ranvier can be prolonged up to 5 to 6 seconds by addition to the medium of minute amounts of certain metal ions. This prolongation involves a change from a triangular to a rectangular configuration. The properties of the prolonged nerve-fiber responses are very similar to those of heart muscle.