Sex Peptide of Drosophila melanogaster

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Science  29 May 1959:
Vol. 129, Issue 3361, pp. 1489-1490
DOI: 10.1126/science.129.3361.1489


All tested stocks of Drosophila melanogaster exhibit a peptide in males but not in females. The failure of some investigators to demonstrate its presence is attributable to their choice of chromatographic solvents. Acid hydrolysis confirms its peptide identity. Its presence in females transformed into males by the mutant tra implicates the sex-determining loci in its formation.