Direct Experimental Observation of Cells in Phenomic Lag

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Science  12 Jun 1959:
Vol. 129, Issue 3363, pp. 1612-1613
DOI: 10.1126/science.129.3363.1612


By employing cells mutating at a very high spontaneous rate and a grid plate containing a medium totally selective against mutant cells, direct microscopic observation was made of mutant cells of recent origin passing through a limited number of phenomic lag divisions.