Influence of Adrenalectomy and Hypophysectomy on Cerebral Serotonin

Science  19 Jun 1959:
Vol. 129, Issue 3364, pp. 1678-1679
DOI: 10.1126/science.129.3364.1678-a


Changes in serous and encephalic serotonin in hypophysectomized or adrenalectomized rats have been observed. Adrenalectomy produces a decrease of serous serotonin and an increase of the serotonin of hemispheres, base, and medulla oblongata; with hypophysectomy, serotonin is also reduced in serum and increased only in the base and medulla oblongata.