Voltage Clamp of Motoneuron Soma

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Science  03 Jul 1959:
Vol. 130, Issue 3366, pp. 38-39
DOI: 10.1126/science.130.3366.38


Concentric microelectrodes were used to voltage-clamp spinal motoneurons. With depolarizing voltage steps, current transients often appear, with some latency and in all-or-none fashion. Voltage-current relations indicate a two- to threefold reduction in resistance between inside and outside when the cell fires. These results suggest that activity does not involve the whole soma-dendritic membrane.