Fate of Frog Embryos Implanted into Forelimbs of Adults

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Science  17 Jul 1959:
Vol. 130, Issue 3368, pp. 166
DOI: 10.1126/science.130.3368.166


No teratoma formation and very little growth and differentiation followed implantation of late gastrula-stage frog embryos into forelimbs of adults. This is attributed to poor blood supply and rigid walls of muscle and bone surrounding the implants. The fate of embryos in nonamputated limbs is compared with that of regeneration-promoting implants in amputated limbs.