Isolation of Several Peptides with Relaxin Activity

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Science  07 Aug 1959:
Vol. 130, Issue 3371, pp. 338
DOI: 10.1126/science.130.3371.338


When a relaxin preparation was subjected to counter-current distribution for 355 transfers in a butanol-trichloroacetic acid system, significant biological activity was found over a band appreciably wider than was expected for a single component. By refractionation of the active band, three peptides with relaxin activity were isolated.