Learning Differences in Two Separated Lines of Mice

See allHide authors and affiliations

Science  21 Aug 1959:
Vol. 130, Issue 3373, pp. 451-452
DOI: 10.1126/science.130.3373.451


Significant differences in conditioning and response topography were obtained with two lines in C57BL/10 mice, suggesting the occurrence of a behavioral mutation. It is suggested that the two lines be classified as substrains. The two substrains would appear to be useful in experiments on the genetics of behavior.