Reports

Left-to-Right Shunt Detection by an Intravascular Electrode with Hydrogen as an Indicator

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Science  18 Sep 1959:
Vol. 130, Issue 3377, pp. 709-710
DOI: 10.1126/science.130.3377.709

Abstract

Hydrogen gas crosses the pulmonary membrane and dissolves in blood, and it therefore appears immediately and in high concentration in the left heart and later and in lower concentration in the right heart. The hydrogen-sensing, platinum black-tipped catheter is uniquely sensitive in detecting the left-to-right shunts.

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