Titration of the Protein Paramyosin

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Science  30 Oct 1959:
Vol. 130, Issue 3383, pp. 1190-1191
DOI: 10.1126/science.130.3383.1190


The titration curve of an aqueous solution of crystalline paramyosin shows a unique buffering zone which can be attributed to a shift in the pK of its glutamic acid residues. A possible explanation of this phenomenon on the basis of the presence of polyanionic segments in the molecule is discussed.