On the Function of Corticothalamic Neurons

See allHide authors and affiliations

Science  01 Jan 1960:
Vol. 131, Issue 3392, pp. 40
DOI: 10.1126/science.131.3392.40


The effect of the synchronous discharge of a large population of corticothalamic neurons on activity within the somatosensory relay nuclei has been studied. Thalamic responses to peripheral nerve stimulation are depressed by activity in corticothalamic neurons. A subconvulsive dose of strychnine, given intravenously, changes this depression to enhancement.