Virulence Transformation of a Trichomonad Protozoan

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Science  05 Feb 1960:
Vol. 131, Issue 3397, pp. 352-353
DOI: 10.1126/science.131.3397.352


Treatment of an avirulent strain of Trichomonas gallinae with a cellfree homogenate of a virulent strain resulted in enhanced virulence as evidenced by the size of lesions produced in mice. Addition of deoxyribonuclease to the homogenate cell mixture blocked the transformation.