Correction of Sample Absorption of Radioactivity

See allHide authors and affiliations

Science  26 Feb 1960:
Vol. 131, Issue 3400, pp. 606
DOI: 10.1126/science.131.3400.606


In the method presented here for the correction of sample absorption of C14 activity, the only requirement is the availability of any C14-labeled compound of sufficiently high specific activity to permit addition, in negligible mass, of a number of counts equal to or greater than that in unknown samples and with solubility characteristics that exclude preferential layering during drying of samples. The principle may be applied to liquid scintillation counting. Absorption curves are dispensed with, and the weights of the assayed samples need not be determined.