Genetic Control of Two γ-Globulin Isoantigenic Sites in Domestic Rabbits

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Science  11 Mar 1960:
Vol. 131, Issue 3402, pp. 738-739
DOI: 10.1126/science.131.3402.738


Results of immunochemical analysis of sera from 335 offspring of 81 litters of rabbits are consistent with the hypothesis that the isoantigenic sites, RGG-I and RGG-II, of the γ-globulins are controlled by a single allelic pair of autosomal genes with both specificities exhibited by the heterozygote. The three genotypes may be designated γII, γIIII, and γIII.