Disulfide Interchange by Ionizing Radiation

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Science  13 May 1960:
Vol. 131, Issue 3411, pp. 1441
DOI: 10.1126/science.131.3411.1441


The irradiation of a soluition of two symmetric disulfides produces detectable amounts of the nonsymmetric mixed disulfide. The effect is abolished by the addition of ethylmaleimide. The finding indicates that radiation caulses a disulfide opening and recombining process which may be of radiobiological interest.