Increased Incidence of Tumor Metastases in Female Mice

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Science  07 Oct 1960:
Vol. 132, Issue 3432, pp. 956-957
DOI: 10.1126/science.132.3432.956


Most of the tumor cells injected into the tail vein of mice fail to survive at the site of arrest in the lungs, but the percentage of surviving cells is higher in females than in males. The surviving cells, however, grow at a similar and constant rate in both sexes.