Acetylcholinesterase Regeneration in Peripheral Nerve after Irreversible Inactivation

Science  28 Oct 1960:
Vol. 132, Issue 3435, pp. 1249-1250
DOI: 10.1126/science.132.3435.1249


The return of acetylcholinesterase activity was studied in several cholinergic structures in the cat after irreversible inactivation by diisopropylfluoro-phosphate. It was found that enzymic activity returned uniformly along the hypoglossal and cervical sympathetic nerve trunks. No evidence for somatoaxonal convection of enzyme was obtained.