Immunological Technique for Protein Isolation

Science  28 Oct 1960:
Vol. 132, Issue 3435, pp. 1252-1253
DOI: 10.1126/science.132.3435.1252


Carefully coagulated antibody or antigen-antibody complexes may be used as specific adsorbents for antigen, and the antigen may be released subsequently by increasing the acidity. No cross adsorption appears to take place. The procedure may prove useful for the isolation of tissue-specific proteins (including those in disease states), toxins, or viruses.