Ribonuclease of Euglena gracilis

Science  16 Dec 1960:
Vol. 132, Issue 3442, pp. 1835-1836
DOI: 10.1126/science.132.3442.1835


An enzyme in extracts of Euglena gracilis splits both purine and pyrimidine internucleotide bonds of ribonucleic acid. Its pH optimum is at 4.5; it is very heat-labile and is rather insensitive to inhibition by metal ions or sulfhydryl group reagents. A partial purification of the enzyme is described.