Effect of Reserpine on Ventricular Escape

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Science  16 Dec 1960:
Vol. 132, Issue 3442, pp. 1836-1837
DOI: 10.1126/science.132.3442.1836


Catecholamine depletion by reserpine diminishes the tendency of the ventricle to escape from vagal suppression. Neither spinal section nor adrenalectomy enhances the reserpine effect. Norepinephrine restores the characteristic occurrence of ventricle escape during vagal stimulation.