Suppressive Effects of 2-Thiouracil on Differentiation and Flowering in Cannabis sativa

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Science  30 Dec 1960:
Vol. 132, Issue 3444, pp. 1943-1944
DOI: 10.1126/science.132.3444.1943


The pyrimidine, 2-thiouracil, partly annuls the effect of photoperiodic induction in the short-day plant, Cannabis sativa L., when it is supplied at the onset of the dark period in quantities of 15-30 µg per plant. This treatment also produces aberrations in cellular differentiation in the leaves. Tracer studies show that 2-thiouracil becomes bound in cellular ribonucleic acid, which suggests that the effects on morphogenesis are due to interference with nucleic acid metabolism.