Learned Behavior of Rhesus Monkeys following Neonatal Bilateral Prefrontal Lobotomy

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Science  30 Dec 1960:
Vol. 132, Issue 3444, pp. 1944-1945
DOI: 10.1126/science.132.3444.1944


Bilateral ablation of dorsolateral frontal cortex in the newborn animal failed to produce the frontal lobe syndrome typical of the adolescent and adult stages. The crucial tests (delayed response, string tests, and discrimination learning) were performed 3 to 4 months postoperatively. At this time, no significant differences between normal animals and animals with prefrontal lesions were found.