Alteration of Mutation Frequency by Treatment with Actinomycin D

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Science  06 Jan 1961:
Vol. 133, Issue 3445, pp. 40
DOI: 10.1126/science.133.3445.40


The frequency of lethal mutations occurring in Drosophila melanogaster was reduced by approximately one-half when irradiated males were treated with actinomycin D, which also inhibited the appearance of melanotic atypical growths in the strain used for the study.