High Incidences of Transmissible Kidney Tumors in Uminoculated Frogs Maintained in a Laboratory

See allHide authors and affiliations

Science  10 Mar 1961:
Vol. 133, Issue 3454, pp. 702-703
DOI: 10.1126/science.133.3454.702


Various workers have shown that the Lucké carcinoma, a transmissible kidney tumor of the leopard frog, occurs spontaneously at low incidence (6.7 percent maximum). However, we have consistently observed much higher incidences (50 percent maximum), a finding of probable significance in the epidemiology and natural transmission of the tumor. Age, metabolic level, and cross infection are being investigated as possible factors in determining the tumor incidence.